Neurofibromatosis Type 1 and Optic Pathway Glioma
نویسندگان
چکیده
منابع مشابه
Detection of tumor progression in optic pathway glioma with and without neurofibromatosis type 1.
BACKGROUND We wanted to determine the sensitivity and specificity of serial changes in visual acuity and visual evoked potentials (VEPs) to detect radiological progression of tumor volume in children with optic pathway gliomas. METHODS From a retrospective review of a cohort of 69 patients, 54 patients met inclusion criteria (31 with primary chemotherapy, 4 with primary radiotherapy, and 19 w...
متن کاملMacrocephaly Is Not a Predictor of Optic Pathway Glioma Development or Treatment in Neurofibromatosis Type 1.
Neurofibromatosis type 1 is a common neurogenetic disorder characterized by significant clinical variability. As such, numerous studies have focused on identifying clinical, radiographic, or molecular biomarkers that predict the occurrence or progression of specific clinical features in individuals with neurofibromatosis type 1. One of these clinical biomarkers, macrocephaly, has been proposed ...
متن کاملGender as a disease modifier in neurofibromatosis type 1 optic pathway glioma.
In his very informative and thoughtful discussion of a patient with copper deficiency, Dr Samuels refers to the checklist concept in considering the differential diagnosis. He cites a Google search of myeloneuropathy and malnutrition as helping in suggesting the diagnosis. He further notes that searching on common nonspecific neurologic signs and symptoms generates exhaustive lists that would n...
متن کاملNeurofibromatosis type 1 and sporadic optic gliomas.
AIMS To compare the natural history of sporadic optic glioma with those associated with neurofibromatosis type 1 (NF1). METHODS Optic glioma cases were identified using both the Manchester Children's Tumour Registry (CTR) and the North West Regional NF1 Database (NF1DB), with detailed information on natural history available from the former (in 34 of 36 cases identified). RESULTS A total of...
متن کاملNon-optic glioma in adults and children with neurofibromatosis 1
BACKGROUND Non-optic gliomas occur in 5% of children with NF1, but little is known about these tumours in adults. We aimed to investigate progression, spontaneous regression and the natural history of non-optic gliomas in adults and compare these findings to the results found in children. RESULTS One thousand seven hundred twenty-two brain MRI scans of 562 unselected individuals with NF1 were...
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ژورنال
عنوان ژورنال: Czech and Slovak Ophthalmology
سال: 2019
ISSN: 1805-4447,1211-9059
DOI: 10.31348/2019/4/4